A synthetic biology postdoctoral position is open in Andrew Hanson's group - 80% research/20% lab management.
The Hanson group is applying synthetic biology approaches to engineering plant and microbial metabolism. Their research aims for utility to agriculture and the bioeconomy. Ongoing projects include:
- Using directed evolution via the E. coli EvolvR system (PMID:30069054) and the yeast OrthoRep system (PMID:30415839) to build more energy-efficient versions of the thiamin synthesis enzyme THI4 (PMID:30337452)
- Using EvolvR to extend the working life of enzymes (and so cut the high energy cost of replacing them)
- Parts-prospecting for enzyme systems that pre-empt or repair damage caused by formaldehyde and other highly reactive metabolic intermediates
- Developing new-to-nature synthetic metabolic pathways that benefit agriculture and the environment
The 20% management component involves overseeing ordering, coordinating performance of everyday tasks by other lab members, and similar routine operations.
We collaborate extensively (via joint Federally-funded projects) and publish with groups at UF, in other US institutions, and in Europe. These groups include synthetic biologists, metabolic engineers, computational biochemists, and plant biochemists.